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Bibliography

2013

V2a Kit - From Vasculogenesis to Angiogenesis

Exosomes from triple-negative breast cancer cells can transfer phenotypic traits representing their cells of origin to secondary cells.
Authors

O'Brien, Keith, et al.

Journal

European Journal Of Cancer 49.8 (2013)

V2a Kit: Vasculogenesis to Angiogenesis used to study the effect of exosomes on vasculogenesis and angiogenesis

The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features.
Authors

Nieminen, Tiina, et al.

Journal

Biochimica Et Biophysica Acta (BBA)-General Subjects 1840.1 (2014)

V2a Kit: Vasculogenesis to Angiogenesis used to determine the biological activity of VEGF

The novel alkylating prodrug melflufen (J1) inhibits angiogenesis
Authors

Strese, Sara, et al.

Journal

Biochemical Pharmacology86.7 (2013): 888-895.

Melflufin can be activated by Aminopeptidase N (APN). APN has been reported to have a functional role in tumour angiogenesis and reported to be over-expressed in human tumours. The V2a Kit: Vasculogenesis to Angiogenesis was used to illustrate the superior anti-angiogenic effect of melflufen compared to melphalan.

Human Umbilical Vein Endothelial Cells

Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis.
Authors

Baker, Ann-Marie, et al.

Journal

Cancer Research 73.2 (2013): 583-594.

Activity of the extracellular matrix-modifying enzyme lysyl oxidaze is essential for stimulating endothelial cells in vitro and angiogenesis in vivo.

AngioKit

A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis.
Authors

Wang, Z., et al.

Journal

Cell Death & Disease 4.9 (2013)

Inhibition of extracellular TG2 protein crosslinking or downregulation of TG2 leads to inhibition of angiogenesis in cell culture, using various models including V2a Kit: Vasculogenesis to Angiogenesis

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